In-vitro ADME Services Market Size, Share, Growth, Global Trends, Industry Analysis and Forecast to 2027

Price: 3200/- USD | Published Date: October 30, 2020 |

The global in-vitro ADME services market size is projected to grow at the CAGR of 6.23% market during 2020-2027 and expected to reach up to $ 4,485.4 million in terms of revenue by 2025. Absorption, distribution, metabolism, and elimination (ADME) describe the disposition of a drug inside the human body. In-vitro ADME services are often sought after for the development and testing of novel drugs. Some of the major factors assisting the growth in demand for In-vitro ADME services are the growing accuracy and predictability of ADME technology and the growing adoption of in-vitro assays for toxicology studies. With the advancement of technology and reliability of ADME testing, its usage in initial screening of compounds and eventual drug development has increased. Conventional methods of drug development are time-consuming, cost-intensive, and also bear the risk of inaccurate results. In addition, a higher risk of failure of in vivo environment in later stages of development has further urged the adoption of in-vitro ADME testing at initial stages of drug development.

Market Insights:

Abbreviation for absorption, distribution, metabolism, and elimination, ADME is a pharmacological term that describes drug disposition in the human body. Thus, collectively ADME is a set of processes that help in analyzing drug performance on human tissue; in-vitro ADME facilitates this testing while avoiding animal testing and faster drug development. Major factors favoring the growth of in-vitro ADME are improved accuracy and predictability of ADME technology, and growing preference for in-vitro testing as against conventional in-vivo methods.

Based on the type of services the global In-Vitro ADME services market is segmented into solution properties, drug absorption & transport, drug metabolism, and drug-drug interaction. Among these, the drug absorption & transport segment was observed to behave the largest revenue share in 2019. Geographically, the global in-vitro ADME services were dominated by Europe. Major factors contributing to the dominance of the European market are intensive research and development activities being carried out in the region for rapid drug discovery and development both at commercial and academic levels. In addition, most of the drug discovery processes in Europe are performed on the domestic front, thus leaving later phases of drug development for outsourcing. Furthermore, the Asia Pacific and Latin America are anticipated to be the fastest progressing markets for in-vitro ADME services, majorly driven by the outsourcing of drug discovery and development processes in the regions.

Market Segment Insights:

Based on the type of services, the global in-vitro ADME services market is classified into solution properties, drug absorption and transport, drug-drug interaction, and drug metabolism services. Among these, drug absorption and transport services currently occupy the largest market share. This service mainly involves testing with parallel artificial membrane permeability screening, MDCK permeability, transporter assay platforms, and Caco-2 permeability screening. One of the critical characteristics in drug absorption and transport is intestinal epithelium permeability which determines the rate and level of human absorption and ultimately affects the bioavailability of a drug candidate. Thus, the key factors assisting the growth of this service market are increasing demand for cost-efficient drug absorption detection services and incessant development in the study of drug absorption methods in preclinical trials.

Global In-vitro ADME Services Market Segmentation:

By Product, 2018–2027 ($ Millon)

  • Drug Absorption and Transport
  • Solution Properties
  • Drug Metabolism
  • Drug-Drug Interaction

By Geography, 2018-2027 ($ Millon)

  • North America
  • Europe
  • Asia Pacific
  • Latin America (LATAM)
  • Middle East and Africa (MEA)

Regional Insights:

In terms of geographical distribution, the global in-vitro ADME services market is studied for North America, Europe, Asia Pacific, Latin America, and Middle East and Africa. In 2019, Europe accounted for the largest market for in-vitro ADME services majorly attributed to large scale research and development activities being performed in the region both at commercial and academic levels. In addition, Asia Pacific is observed to be the fastest-growing market for the in-vitro ADME service. This region is likely to progress with an increase in drug discovery efforts in the pharmaceutical industry and large-scale outsourcing from North America. Markets of Latin America and Middle East and Africa will also witness significant growth during the forecast period. Countries such as Brazil, Argentina and Mexico will benefit from the recent trend of outsourcing research and development processes for the purpose of cost containment.

Market Competition Assessment:

Some of the major players operating in the global in-vitro ADME services market are Sigma-Aldrich Co. LLC/ MilliporeSigma, Aptagen, LLC, Covance, Inc., WuXiAppTec, In Vitro ADMET Laboratories, LLC, and others.

List of Key Companies:

  • Absorption Systems LP
  • Aptagen, LLC
  • Sigma-Aldrich Co. LLC/ MilliporeSigma
  • BioTeSys GmbH
  • WuXiAppTec
  • Cyprotex PLC
  • Centrillion Technology Holdings Ltd.
  • Covance, Inc.
  • In Vitro ADMET Laboratories, LLC
  • XenoTech, LLC

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Key Questions Answered by In-vitro ADME Services Market Report

  • Global in-vitro adme services market forecasts from 2020-2027
  • Regional in-vitro adme services market forecasts from 2020-2027 covering Asia-Pacific, North America, Europe, Middle East and Africa, and Latin America
  • Country level forecasts from 2020-2027 covering 15 major countries from aforementioned regions
  • In-vitro ADME Services submarket forecasts from 2020-2027 covering the market by product, and geography
  • Various industry models such as SWOT analysis, Pestle Analysis, Porter’s Five Force model, Value Chain Analysis pertaining to in-vitro adme services market
  • Analysis of the key factors driving and restraining the growth of the global, regional and country level in-vitro adme services markets from 2020-2027
  • Competitive Landscape and market positioning of top 10 players operating in the in-vitro adme services market

(Reports will be updated due to COVID-19 impacts on the market)

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Table of Content:


Chapter 1 Preface
1.1 Report Description
1.1.1 Purpose of the Report
1.1.2 Target Audience
1.1.3 USP and Key Offerings
1.2 Research Scope
1.3 Research Methodology
1.3.1 Phase I – Secondary Research
1.3.2 Phase II – Primary Research
1.3.3 Phase III – Expert Panel Review
1.3.4 Assumptions
Chapter 2 Executive Summary
2.1 Global In-Vitro ADME Services Market Portraiture
2.2 Global In-Vitro ADME Services Market, by Type, 2019 ($ Million)
2.3 Global In-Vitro ADME Services Market, by Geography, 2019 (Value %)
Chapter 3 Market Dynamics: In Vitro ADME Services Market
3.1 In Vitro ADME Services Market Analysis
3.2 Future Market Trend: In Vitro ADME Services
3.3 Regulatory Market Scenario
3.4 Mergers and Acquisition
3.5 Market Dynamics
3.5.1 Market Divers
3.5.1.1 Raising ethical concern regarding animal testing
3.5.1.2 Advancement in R&D for early detection of toxicity
3.5.1.3 Lack of comprehensive databases of in-vitro test methods
3.5.2 Challenges
3.5.2.1 Due to predictive paradise, decline in use of in vitro testing
3.5.2.2 In Vitro Models inability to Detect Autoimmunity & Immunostimulation
3.5.3 Opportunities
3.5.3.1 Surge in demand of in vitro ( pre-clinical ADME Tox) method for drug development and screening and various toxicology programs
3.6 Attractive Investment Proposition
3.7 Market Share Analysis: Key In- Vitro ADME Service Providers, 2019 (Value %)
Chapter 4 Global In-Vitro ADME Services Market Analysis, by Type, 2019-2027 ($ Million)
4.1 Introduction
4.2 Solution Properties
4.3 Drug Absorption & Transport
4.4 Drug Metabolism
4.5 Drug-Drug Interactions
Chapter 5 Global In-Vitro ADME Services Market, by Geography, 2018 – 2027 (US$ Million)
5.1 Preface
5.2 North America (U.S. & Canada)
5.3 Europe (U.K., Germany & Rest of Europe)
5.4 Asia Pacific (China, Japan, Singapore, South Korea and Rest of APAC)
5.5 Latin America (Mexico, Brazil and Rest of LATAM)
5.6 Middle East and Africa
Chapter 6 Company Profiles
6.1 Absorption Systems LP
6.2 Albany Molecular Research, Inc. (AMRI)
6.3 Aptagen, LLC
6.4 BIOalternatives SAS
6.6 Sigma-Aldrich Co. LLC/ MilliporeSigma
6.8 BioTeSys GmbH
6.9 Calvert Labs
6.10 XenoTech, LLC
6.11 Cyprotex PLC
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