The global tangential flow filtration market size is projected to grow at a significant CAGR of over 12% during the forecast period from 2022 to 2028. The increasing adoption of the technology for biopharmaceuticals that are used for the treatment of various types of diseases such as cancer, diabetes, and rheumatoid arthritis is a major factor to drive the market growth. Furthermore, technological advancement, increasing investment, and the growing adoption of single-use technologies due to their various benefits such as increased flexibility, reduced cross-contamination, and decreased process time are further anticipated to fuel the market. In addition, the growing therapeutic application of recombinant proteins is anticipated to provide some opportunities for the payers.
Market Drivers:
Increasing Biopharmaceutical Production: The biopharmaceutical industry is experiencing significant growth, driven by the development and production of biologics, including monoclonal antibodies, recombinant proteins, and vaccines. Tangential flow filtration is a critical step in the purification and concentration of these biopharmaceutical products, making it an essential technology in bioprocessing.
Growing Demand for Biologics: Biologics are gaining popularity in the healthcare sector due to their specificity and effectiveness in treating various diseases, including cancer, autoimmune disorders, and infectious diseases. Tangential flow filtration plays a crucial role in the downstream processing of biologics, enabling the removal of impurities, such as aggregates, host cell proteins, and viruses, and achieving high product purity.
Stringent Regulatory Requirements: The biopharmaceutical industry is highly regulated, and strict quality control measures are in place to ensure product safety and efficacy. Tangential flow filtration helps meet these regulatory requirements by providing effective and reliable methods for process purification, concentration, and virus clearance, ensuring the production of safe and high-quality biopharmaceutical products.
Advancements in TFF Technologies: Technological advancements in tangential flow filtration have improved its efficiency, scalability, and ease of use. Enhanced membrane materials, filter designs, and automation systems have contributed to better process performance, higher productivity, and reduced operating costs. These advancements have driven the adoption of TFF in various bioprocessing applications.
Increasing Research and Development Activities: Research and development efforts in biotechnology and pharmaceutical companies are driving the need for efficient downstream processing techniques, including tangential flow filtration. The continuous quest for innovation and optimization of bioprocessing workflows fuels the demand for TFF systems and consumables.
Growing Adoption of Single-Use Systems: The trend towards single-use technologies in bioprocessing has positively impacted the TFF market. Single-use TFF systems offer advantages such as reduced cross-contamination risks, faster turnaround times, and lower capital investments. The ease of implementation and scalability of single-use TFF systems have led to their widespread adoption in the biopharmaceutical industry.
Increasing Focus on Cost Efficiency: Biopharmaceutical manufacturers are continuously seeking ways to optimize their production processes and reduce costs. Tangential flow filtration offers advantages in terms of process efficiency, reduced labor requirements, and higher product recovery rates. The implementation of TFF can contribute to cost savings and improved overall process economics.
Market Snapshot:
| Benchmark Year | 2022 | ||
| Market Size | lock | ||
| Market Growth (CAGR) | > 12% (2023-2030) | ||
| Largest Market Share | lock | ||
| Analysis Period | 2020-2030 | ||
| Market Players | Danaher Corporation, Sartorius AG, Parker-Hannifin Corporation, Alfa Laval AG, and Merck KGaA |
Market Insights:
By technology, the microfiltration technology segment held the largest market share in 2021
The global tangential flow filtration market is bifurcated into product, technology, application, end-user, and geography. On the basis of technology, the market is further segmented into ultrafiltration, microfiltration, nanofiltration, and others. The microfiltration segment dominated the global market in 2021 and accounted to hold a significant revenue share of around 1/3 of the market share. The segment growth is majorly attributed to the widespread use of the technology during the cell separation processes. Furthermore, the technology is also used in protein fractionation, microbial removal and pretreatment of other membranes, which is further anticipated to propel the segment growth. On the flip side, the nanofiltration segment is accounted to grow at the highest growth rate over the forecast period.
By end-user, the pharmaceuticals & biotechnology companies segment is estimated to dominate the global market by 2028
On the basis of end-user, the market is segmented into pharmaceutical & biotechnology companies, CRO & CMO, and academic institutes & research laboratories. The pharmaceuticals & biotech companies segment dominated the global tangential flow filtration market in 2021 and expected to hold a significant revenue share of over 1/3 of the global market by the end of the analysis period. The increasing investment in research & development and the growing drug discovery activities are some major factors to drive the segment growth. On the other hand, the CROs and CMOs segment is estimated to grow at the highest growth rate over the forecast period. The increasing use of single-use technologies and the growing demand for biopharmaceuticals are some major factors to fuel the segment growth over the forecast period.
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The tangential flow filtration comprehensive study analyzes industry trends, market size, competitive analysis, and market forecast – 2022 to 2028. Research Corridor report provides detailed premium insight into the global market and reveals the potential revenue streams, commercial prospects, market drivers, challenges, opportunities, issues, and events affecting the industry. In addition, the report has a dedicated section covering market forecasts and analysis for leading geographies, profiles of major companies operating in the market and expert opinion obtained from interviews with industry executives and experts from prominent companies.
The tangential flow filtration market research report presents the analysis of each segment from 2019 to 2028 considering 2021 as the base year for the research. The compounded annual growth rate (CAGR) for each respective segment is calculated for the forecast period from 2022 to 2028.
Historical & Forecast Period
- 2019-20 – Historical Year
- 2021 – Base Year
- 2022-2028 – Forecast Period
Market Segmentation:
By Product:
- Single-use Tangential Systems
- Reusable Tangential Systems
- Membrane Filters
- Polyethersulfone (PES)
- Polyvinylidene Difluoride (PVDF)
- Polytetrafluoroethylene (PTFE)
- Mixed Cellulose Ester & Cellulose Acetate
- Polycarbonate Tracked Etched (PCTE)
- Regenerated Cellulose
- Others
- Filtration Accessories
By Technology:
- Ultrafiltration
- Microfiltration
- Nanofiltration
- Others
By Application:
- Protein Purification
- Vaccine and Viral Vectors
- Antibody Purification
- Raw Material Filtration
- Others
By End-User:
- Pharmaceutical & Biotechnology Companies
- CROs & CMOs
- Academic Institutes & Research Laboratories
By Region:
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East & Africa
Geographic Coverage:
Geographically, the tangential flow filtration market report comprises dedicated sections centering on the regional market revenue and trends. The tangential flow filtration market has been segmented on the basis of geographic regions into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa. The tangential flow filtration market has been extensively analyzed on the basis of various regional factors such as demographics, gross domestic product (GDP), inflation rate, acceptance, and others. Tangential flow filtration market estimates have also been provided for the historical years 2019 & 2020 along with forecasts for the period from 2022 – 2028.
Competitive Assessment:
Some of the major market players operating in the global tangential flow filtration market are Danaher Corporation, Sartorius AG, Parker-Hannifin Corporation, Alfa Laval AG, and Merck KGaA. Companies are exploring markets through expansion, new investment, the introduction of new services, and collaboration as their preferred strategies. Players are exploring new geography through expansion and acquisition to gain a competitive advantage through joint synergy.
Key Companies:
- Danaher Corporation
- Sartorius AG
- Parker-Hannifin Corporation
- Alfa Laval AG
- Merck KGaA
- Repligen Corporation
- ABEC, Inc.
- Sterlitech Corporation
- Synder Filtration, Inc.
- Meissner Filtration Products, Inc.
Key Questions Answered by Tangential Flow Filtration Market Report
- Global tangential flow filtration market forecasts from 2022-2028
- Regional market forecasts from 2022-2028 covering Asia-Pacific, North America, Europe, Middle East & Africa, and Latin America
- Country-level forecasts from 2022-2028 covering 15 major countries from the regions as mentioned above
- Tangential flow filtration submarket forecasts from 2022-2028 covering the market by product, technology, application, end-user, and geography
- Various industry models such as SWOT analysis, Value Chain Analysis about the market
- Analysis of the key factors driving and restraining the growth of the global, regional, and country-level tangential flow filtration markets from 2022-2028
- Competitive Landscape and market positioning of the top 10 players operating in the market
1. Preface
1.1. Report Description
1.1.1. Purpose of the Report
1.1.2. Target Audience
1.1.3. USP and Key Offerings
1.2. Research Scope
1.3. Research Methodology
1.3.1. Phase I – Secondary Research
1.3.2. Phase II – Primary Research
1.3.3. Phase III – Expert Panel Review
1.4. Assumptions
2. Executive Summary
2.1. Global Tangential Flow Filtration Market Portraiture
2.2. Global Tangential Flow Filtration Market, by Product, 2021 (USD Mn)
2.3. Global Tangential Flow Filtration Market, by Technology, 2021 (USD Mn)
2.4. Global Tangential Flow Filtration Market, by Application, 2021 (USD Mn)
2.5. Global Tangential Flow Filtration Market, by End-User, 2021 (USD Mn)
2.6. Global Tangential Flow Filtration Market, by Geography, 2021 (USD Mn)
3. Global Tangential Flow Filtration Market Analysis
3.1. Tangential Flow Filtration Market Overview
3.2. Market Inclination Insights
3.3. Market Dynamics
3.3.1. Drivers
3.3.2. Challenges
3.3.3. Opportunities
3.4. Attractive Investment Proposition
3.5. Competitive Analysis
3.6. Porter’s Five Force Analysis
3.6.1. Bargaining Power of Suppliers
3.6.2. Bargaining Power of Buyers
3.6.3. Threat of New Entrants
3.6.4. Threat of Substitutes
3.6.5. Degree of Competition
3.7. COVID-19 Impact Analysis
4. Global Tangential Flow Filtration Market By Product, 2019 – 2028 (USD Mn)
4.1. Overview
4.2. Single-use Tangential Flow Filtration Systems
4.3. Reusable Tangential Flow Filtration Systems
4.4. Membrane Filters
4.4.1. Polyethersulfone (PES)
4.4.2. Polyvinylidene Difluoride (PVDF)
4.4.3. Polytetrafluoroethylene (PTFE)
4.4.4. Mixed Cellulose Ester & Cellulose Acetate
4.4.5. Polycarbonate Tracked Etched (PCTE)
4.4.6. Regenerated Cellulose
4.4.7. Others
4.5. Filtration Accessories
5. Global Tangential Flow Filtration Market By Technology, 2019 – 2028 (USD Mn)
5.1. Overview
5.2. Ultrafiltration
5.3. Microfiltration
5.4. Nanofiltration
5.5. Others
6. Global Tangential Flow Filtration Market By Application, 2019 – 2028 (USD Mn)
6.1. Overview
6.2. Protein Purification
6.3. Vaccine and Viral Vectors
6.4. Antibody Purification
6.5. Raw Material Filtration
6.6. Others
7. Global Tangential Flow Filtration Market By End-User, 2019 – 2028 (USD Mn)
7.1. Overview
7.2. Pharmaceutical & Biotechnology Companies
7.3. CROs & CMOs
7.4. Academic Institutes & Research Laboratories
8. North America Tangential Flow Filtration Market Analysis and Forecast, 2019 – 2028 (USD Mn)
8.1. Overview
8.2. North America Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
8.3. North America Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
8.4. North America Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
8.5. North America Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
8.6. North America Tangential Flow Filtration Market by Country, (2019-2028 USD Mn)
8.6.1. U.S.
8.6.1.1. U.S. Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
8.6.1.2. U.S. Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
8.6.1.3. U.S. Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
8.6.1.4. U.S. Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
8.6.2. Canada
8.6.2.1. Canada Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
8.6.2.2. Canada Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
8.6.2.3. Canada Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
8.6.2.4. Canada Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
9. Europe Tangential Flow Filtration Market Analysis and Forecast, 2019 – 2028 (USD Mn)
9.1. Overview
9.2. Europe Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
9.3. Europe Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
9.4. Europe Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
9.5. Europe Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
9.6. Europe Tangential Flow Filtration Market by Country, (2019-2028 USD Mn)
9.6.1. Germany
9.6.1.1. Germany Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
9.6.1.2. Germany Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
9.6.1.3. Germany Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
9.6.1.4. Germany Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
9.6.2. U.K.
9.6.2.1. U.K. Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
9.6.2.2. U.K. Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
9.6.2.3. U.K. Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
9.6.2.4. U.K. Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
9.6.3. France
9.6.3.1. France Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
9.6.3.2. France Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
9.6.3.3. France Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
9.6.3.4. France Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
9.6.4. Spain
9.6.4.1. Spain Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
9.6.4.2. Spain Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
9.6.4.3. Spain Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
9.6.4.4. Spain Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
9.6.5. Italy
9.6.5.1. Italy Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
9.6.5.2. Italy Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
9.6.5.3. Italy Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
9.6.5.4. Italy Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
9.6.6. Rest of Europe
9.6.6.1. Rest of Europe Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
9.6.6.2. Rest of Europe Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
9.6.6.3. Rest of Europe Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
9.6.6.4. Rest of Europe Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
10. Asia Pacific Tangential Flow Filtration Market Analysis and Forecast, 2019 – 2028 (USD Mn)
10.1. Overview
10.2. Asia Pacific Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
10.3. Asia Pacific Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
10.4. Asia Pacific Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
10.5. Asia Pacific Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
10.6. Asia Pacific Tangential Flow Filtration Market by Country, (2019-2028 USD Mn)
10.6.1. China
10.6.1.1. China Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
10.6.1.2. China Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
10.6.1.3. China Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
10.6.1.4. China Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
10.6.2. Japan
10.6.2.1. Japan Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
10.6.2.2. Japan Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
10.6.2.3. Japan Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
10.6.2.4. Japan Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
10.6.3. India
10.6.3.1. India Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
10.6.3.2. India Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
10.6.3.3. India Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
10.6.3.4. India Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
10.6.4. Rest of Asia Pacific
10.6.4.1. Rest of Asia Pacific Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
10.6.4.2. Rest of Asia Pacific Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
10.6.4.3. Rest of Asia Pacific Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
10.6.4.4. Rest of Asia Pacific Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
11. Latin America (LATAM) Tangential Flow Filtration Market Analysis and Forecast, 2019 – 2028 (USD Mn)
11.1. Overview
11.2. Latin America Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
11.3. Latin America Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
11.4. Latin America Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
11.5. Latin America Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
11.6. Latin America Tangential Flow Filtration Market by Country, (2019-2028 USD Mn)
11.6.1. Brazil
11.6.1.1. Brazil Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
11.6.1.2. Brazil Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
11.6.1.3. Brazil Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
11.6.1.4. Brazil Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
11.6.2. Mexico
11.6.2.1. Mexico Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
11.6.2.2. Mexico Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
11.6.2.3. Mexico Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
11.6.2.4. Mexico Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
11.6.3. Rest of Latin America
11.6.3.1. Rest of Latin America Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
11.6.3.2. Rest of Latin America Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
11.6.3.3. Rest of Latin America Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
11.6.3.4. Rest of Latin America Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
12. Middle East and Africa Tangential Flow Filtration Market Analysis and Forecast, 2019 – 2028 (USD Mn)
12.1. Overview
12.2. MEA Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
12.3. MEA Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
12.4. MEA Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
12.5. MEA Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
12.6. Middle East and Africa Tangential Flow Filtration Market, by Country, (2019-2028 USD Mn)
12.6.1. GCC
12.6.1.1. GCC Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
12.6.1.2. GCC Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
12.6.1.3. GCC Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
12.6.1.4. GCC Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
12.6.2. South Africa
12.6.2.1. South Africa Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
12.6.2.2. South Africa Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
12.6.2.3. South Africa Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
12.6.2.4. South Africa Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
12.6.3. Rest of MEA
12.6.3.1. Rest of MEA Tangential Flow Filtration Market by Product, (2019-2028 USD Mn)
12.6.3.2. Rest of MEA Tangential Flow Filtration Market by Technology, (2019-2028 USD Mn)
12.6.3.3. Rest of MEA Tangential Flow Filtration Market by Application, (2019-2028 USD Mn)
12.6.3.4. Rest of MEA Tangential Flow Filtration Market by End-User, (2019-2028 USD Mn)
13. Company Profiles
13.1. Danaher Corporation
13.1.1. Business Description
13.1.2. Financial Health and Budget Allocation
13.1.3. Product Positions/Portfolio
13.1.4. Recent Development
13.1.5. SWOT Analysis
13.2. Sartorius AG
13.2.1. Business Description
13.2.2. Financial Health and Budget Allocation
13.2.3. Product Positions/Portfolio
13.2.4. Recent Development
13.2.5. SWOT Analysis
13.3. Parker-Hannifin Corporation
13.3.1. Business Description
13.3.2. Financial Health and Budget Allocation
13.3.3. Product Positions/Portfolio
13.3.4. Recent Development
13.3.5. SWOT Analysis
13.4. Alfa Laval AG
13.4.1. Business Description
13.4.2. Financial Health and Budget Allocation
13.4.3. Product Positions/Portfolio
13.4.4. Recent Development
13.4.5. SWOT Analysis
13.5. Merck KGaA
13.5.1. Business Description
13.5.2. Financial Health and Budget Allocation
13.5.3. Product Positions/Portfolio
13.5.4. Recent Development
13.5.5. SWOT Analysis
13.6. Repligen Corporation
13.6.1. Business Description
13.6.2. Financial Health and Budget Allocation
13.6.3. Product Positions/Portfolio
13.6.4. Recent Development
13.6.5. SWOT Analysis
13.7. ABEC, Inc.
13.7.1. Business Description
13.7.2. Financial Health and Budget Allocation
13.7.3. Product Positions/Portfolio
13.7.4. Recent Development
13.7.5. SWOT Analysis
13.8. Sterlitech Corporation
13.8.1. Business Description
13.8.2. Financial Health and Budget Allocation
13.8.3. Product Positions/Portfolio
13.8.4. Recent Development
13.8.5. SWOT Analysis
13.9. Synder Filtration, Inc.
13.9.1. Business Description
13.9.2. Financial Health and Budget Allocation
13.9.3. Product Positions/Portfolio
13.9.4. Recent Development
13.9.5. SWOT Analysis
13.10. Meissner Filtration Products, Inc.
13.10.1. Business Description
13.10.2. Financial Health and Budget Allocation
13.10.3. Product Positions/Portfolio
13.10.4. Recent Development
13.10.5. SWOT Analysis
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